YOUR FUNDRAISING STORIES
What is triple-negative breast cancer?
About 10 to 20 percent of breast cancers are triple-negative.
Knowing breast cancer basics can help you understand how triple-negative breast cancer is different from other types of breast cancer. Doctors search for the presence or absence of three receptors, proteins that live inside or on the surface of a cell and bind to something in the body to cause the cell to react. You may have heard of the oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2).
In oestrogen receptor-positive breast cancer, progesterone receptor-positive breast cancer and HER2 positive breast cancer, treatments prevent, slow or stop cancer growth with medicines that target those receptors. But triple-negative breast cancers need different types of treatments because they are oestrogen receptor negative, progesterone receptor negative and HER2 negative. Medicines like tamoxifen, which targets the oestrogen receptor, and trastuzumab (Herceptin), which targets HER2, are not helpful in treating triple-negative breast cancer. Instead, chemotherapy has been shown to be the most effective treatment for triple-negative breast cancer.
Researchers are working to improve their understanding of the biology of triple-negative breast cancers, how these types of cancers behave and what puts people at risk for them. Their goals are to find out the best ways to use treatments that already exist and to develop new ones.
Understanding the ‘Basal-like’ Subtype
Most triple-negative breast cancers have a basal-like cell pattern. This term means the cells look like the basal cells that line the breast ducts, the tubes in the breast where milk travels.
Basal-like breast cancers tend to over express, or make too much of, certain genes that encourage cancer growth. Not all triple-negative breast cancers are basal-like, and not all basal-like breast cancers are triple-negative. About 70 to 90 percent of triple-negative breast cancers are basal-like.
Doctors choose treatments because the cancer is triple-negative, not because it is basal-like. The basal status of the cancer does not factor into treatment decisions.
Myth About Triple-Negative Breast Cancer
MYTH – Women with triple-negative breast cancer can have the same treatments as all other women with breast cancer.
FACT – Many people do not understand that there are different kinds of breast cancer. Even some women who have had breast cancer do not understand the differences between triple negative breast cancers and breast cancers that are hormone receptor-positive or HER2 positive.
Researchers are still learning why some women are more likely than others to develop triple-negative breast cancer. Research supports a relationship between risk and your genes, age, race and ethnicity.
Breast Cancer Gene Mutations
Everyone has BRCA1 and BRCA2 genes, which we get from our mother and father. When they work properly, these genes prevent the development of cancers. However, less than 10 percent of people with breast cancer are born with a mutation, or abnormality, in BRCA1 or BRCA2.
Triple-Negative Breast Cancer Risk Factors
If you are born with a BRCA1 or BRCA2 gene mutation, you are at increased risk for developing breast, ovarian and other cancers throughout your life. The BRCA1 mutation puts you at higher risk for developing a basal-like breast cancer. Scientists are still trying to find out why BRCA1 mutations increase the risk of developing triple-negative breast cancer. Keep in mind, not all breast cancers from BRCA mutations are triple-negative. In fact, BRCA2 mutations are more likely to be present in oestrogen receptor-positive breast cancer. If you have a family history of breast cancer, you and your relatives could carry a BRCA1 or BRCA2 mutation. You could also be the first person in your family known to develop breast cancer because of a BRCA mutation. Knowing your BRCA status can help you and your doctors discuss an effective treatment plan and learn ways to reduce your risk for recurrence. A genetic counsellor can talk with you about genetic testing. Anna was tested and was NOT BRCA positive, but this is important information which can affect treatment options.
Age, Race or Ethnicity
Several studies suggest that being premenopausal, African-American, Latina or Caribbean increases risk of developing basal-like or triple-negative breast cancer. Among African-American women who develop breast cancer, there is an estimated 20 to 40 percent chance of the breast cancer being triple-negative. Researchers do not yet understand why premenopausal women and women in some ethnic groups have higher rates of triple negative breast cancer.
Resources for more information:Continue reading →
Bollywood fundraiser to fight breast cancer
How’s this for an idea 💡 Host a Bollywood themed summer party at your home, ask everyone to dress up, book dhol drummers, dancers and Henna artists, serve up bowls of delicious curry AND raise money for those affected by breast cancer by charging for tickets and selling raffle tickets and pink ribbon brooches …. that’s EXACTLY what Sharon and Sharon (Combined Knowledge Ltd) did at the weekend and it was a brilliant day/night attended by friends and family including our very own Patron Lisa Lashes!!! Over £1,300 was raised for the Pink Ribbon Foundation 🎀 Just goes to show that ANYONE can raise money for a good cause, without the need to hire a venue – imagination and a desire to support is all you need. Thank you to everyone involved: Oh My Dhol drummers, Creative Edge Dance Academy dancers and The New Sunar Gow, Lutterworth.
Raffle prizes kindly donated by: Holiday Inn London Kensington High Street, Moda in Pelle, Lindex UK, Paul Mitchell, Rapesco Office Products and FDD International.
Continue reading →
The Niesen Stairway-Run
As a company our friends at Corinthian Sports Ltd wanted to find a challenge that would be both difficult mentally and physically (and something a bit out of the norm) in support of their Charity of the Year, the Pink Ribbon Foundation.
The Niesen Stairway-Run seemed like the perfect race to participate in, and it proved to be a great experience for them all. With 11,674 steps and an elevation gain of 1669m the staircase, which runs alongside the funicular, is the longest in the world. Runners start every 20 seconds with the aim of completing this 3.5km trail, known as “Switzerland’s Pyramid”.
Every step taken was to help raise money for those who have been affected by breast cancer. It was certainly a challenge and we are extremely proud of the team for getting to the top – a rewarding experience for a great cause. Thank you!
Continue reading →
SFC Academy host charity 5-a-side tournament in memory of Lynsey Joseph
Our heartfelt thanks go to Scott and everyone at SFC Academy who recently held a fantastic family filled charity day to honour a wonderful lady and great friend who sadly battled and lost her fight to cancer.
The SFC Academy decided to raise funds for the Pink Ribbon Foundation in order to support other women (and a smaller percentage of men) also going through breast cancer. Their fantastic 5-a-side tournament (in memory of Lynsey Joseph) and family fun day which incorporated bouncy castle, glitter tattoos, hair braiding, food stands and raffle, helped them to raise the fantastic amount of £8,745 for the Foundation!!!
⚽️🎀⚽️ A great day was had by all and we are truly thankful for their AMAZING support. Here’s to next year’s charity tournament!!!Continue reading →
Wendy Brunt’s 30KM Quadrathlon challenge
Our thanks go to Wendy Brunt who after being diagnosed with breast cancer just last year and only 30 weeks after treatment, finished a 30KM Quadrathlon (2 km swim -100 lengths, a 5 KM horse ride, a 7KM run AND a 16KM cross country bike ride all on the SAME DAY) in aid of the Pink Ribbon Foundation raising over £1,000 to support others affected by the disease!
Wendy fully appreciated the care that she received whilst going through treatment, from hospital staff, family and friends and realises that not everyone is so lucky and it was this empathy that spurred her on to take on the challenge and raise awareness and money.
We are extremely grateful for her support and in awe of her achievement. If you are able to support her fundraising, please take a look at her Just Giving page: https://www.justgiving.com/fundraising/Wendy-Brunt1?utm_campaign=lc_frp_share_transaction_fundraiser_page_donation_received_-_nth_donation&utm_content=1bbbc500-37e9-4cdd-94bf-ef12a099513e&utm_medium=email&utm_source=postoffice&utm_term=1559920718432Continue reading →
River Aesthetics Raise over £10,000 hosting a Ladies Lunch
On the 1 May the lovely ladies at River Aesthetics raised £10,784 for the Pink Ribbon Foundation by hosting an amazing Ladies Charity Lunch at the Haven Hotel in Sandbanks. Our thanks go to the 80 heroes who attended and helped raise this phenomenal amount – we are tickled pink!! Thanks also to our Patron Anthea Turner for hosting the event and to all the support given by the following companies and individuals:
Flamingo Candles, Dorset Wedding Photographer, Champneys Spas, Me Me London, Edwards Flowers, Adele Parks, Sebo UK, Calum Best, Skinade, Rick Stein Restaurants, London Medical Concierge, Sinclair Pharma APAC, Playboy Club London, FJB Hotels, Hilton London Syon, Loch Fyne Restaurants, Chewton Glen, Dr Michael Mosley, Conde Nast, Zenflore UK, HNB Hair Salon, Positive Communications, Stanwells Boutique and Barclays UK for their contribution to the funds raised!
#CharityLunch #pinkribbon #PinkRibbonFoundation #RiverAesthetics #centreofexcellence #AestheticsMedicine #InstaBeauty #TeamRiver #beauty #aestheticstrainer #positivity #teamprf #aestheticsdoctor #aestheticsexpert #charitytuesday
Continue reading →
Our very own Lisa Allen jumps 13,000ft to support those affected by breast cancer
After two failed attempts Lisa Allen, Head of Corporate Partnerships, PR and Events at the Pink Ribbon Foundation finally managed to complete her charity skydive on the 28 April in aid of the Foundation. Having convinced a small team from corporate partner Valspar Paint UK, plus upcycler Lynne Lambourne and TV carpenter and presenter Wayne Perrey to join her (amazing powers of persuasion), the team bravely skydived 13,000ft to raise awareness and money for those affected by breast cancer. The team have between them raised over £6,000 for the charity, which makes all the nerves worth it. Our thanks go to all of the instructors at Hinton Sky Diving Centre who got everyone down safely and inspired such confidence and calm, making it a truly memorable experience for all the participants and to Kimberley at Skyline for all of the support and organising in the lead up to the day. Biggest thanks must go to the wonderful people who jumped in aid of the Pink Ribbon Foundation, to those who cheered and supported on the day and to everyone who has made a donation to one of the fundraising pages to support their FUNdraising efforts! You are all fabulous!
If you want to enjoy the same exhilarating feeling of a skydive – flying through the clouds from over 10,000ft at up to 120 mph – then why not jump for our charity?! This incredible challenge will give you the biggest adrenaline rush you could ever imagine as you soar through the air knowing that you have helped raised invaluable funds for the Pink Ribbon Foundation. The tandem jump is the most popular of all skydives, it requires just 30 minutes training before you are strapped to your fully qualified BPA instructor who does all the hard work so you can enjoy the ride! For more information and to make a booking go to: http://www.skylineparachuting.co.uk/bookingentry.aspx?clientID=81627 or send us a email.
Continue reading →
Watsonians Rugby Club
Thank you to everyone at the Watsonians Rugby Club for raising an amazing £600 for the Pink Ribbon Foundation during their recent charity Ladies Lunch. The pre-match lunches are normally attended by men, so they decided to give the Ladies the chance to have some fun during the last home game of the season on the 2nd March. Many small local businesses attended the fundraising event so there were plenty of opportunities to browse and shop before sitting down to a delicious three course meal. There was also a raffle and some fun games held during the afternoon. We thank them for their wonderful support, which will make a difference to those affected by breast cancer.Continue reading →
Archer Street Soho raised £503
A massive thank you to the team Archer Street Soho for raising an incredible £503 for the Pink Ribbon Foundation. The theme for their Valentine’s Day celebrations this year was “Pretty in Pink” and guests were invited to wear something pink to receive a complimentary “Pretty in Pink” cocktail. Proceeds from sales of the “Pretty in Pink” cocktail sold on night were donated to the Foundation, as well donations taken for pink ribbons. Thank you to all the staff at Archer Street and their customers for your generous support!! (Special shout out to Head Bartender Aina who donated her service charge from the Valentine’s Day event to the Pink Ribbon Foundation 😘). #london #soho #pinkribbon #cocktail #prettyinpink #charity #dogood #valentinesday #fundraising #drinkpink #pinkribbonfoundation #archerstreetsohoContinue reading →
Yvonne and Fraser Thomas
Congratulations to Yvonne and Fraser Thomas from Stranraer, Scotland who braved the cold on New Years Day to raise money for the Pink Ribbon Foundation and a local breastfeeding group for babies. Their dip on the shore of Loch Ryan raised £340 to be split between the two charities. They were joined by 30 people, taking part in this annual event to raise money and awareness for different charities – all were cheered on by family and friends and the morning was made extra special for Yvonne and Fraser as they were supported by their first baby granddaughter, Eden. Thank you for choosing to support the work of the Pink Ribbon Foundation!Continue reading →